The latest Hitman: Absolution trailer from Square Enix reveals Blake Dexter, an arms dealer who will almost certainly be snuffed out at the hands of Agent 47. The trailer establishes some background on who Dexter is and why he's on the ICA watch list. Definitely seems like a prime target for 47's garrote.
A press release describes Dexter as "a twisted character and maybe the most vicious adversary Agent 47 has faced yet." He's an arms dealer disguised as a wealthy industrialist and he serves as a primary antagonist in the game. Best of all, Dexter is voiced and performance captured by Keith Carradine, who you may remember as Wild Bill Hickock from the early episodes of HBO's Deadwood.
Hitman: Absolution comes to PlayStation 3, Xbox 360, and PC platforms on November 20, 2012.