Upcoming civil planning simulator SimCity will require EA's Origin and always-on Internet, but you'll be able to buy it on other downloadable services. Basically, no matter where you buy the game, you'll need an Origin log-in to play it. The game's focus on multiplayer and the world-wide economy require an internet connection in order to function.
Required internet aside, the game itself sounds amazing, and uses the Glassbox ending to simulate a huge array of different aspects of a city, including the economy, traffic patterns, and daily lives of the citizens of your city. Check out the video under the "Read More" tag for a look into SimCity.