If you're looking for a game featuring repugnant half-human, half-beast creatures, you don't have to wait for the video game adaptation of The Island of Doctor Moreau. Instead, you can just play Red Dead Redemption, where game-glitches have created the following kill-it-with-fire abominations:
Bird-Men of the Old West
I haven't noticed a lot of glitches in Red Dead, and it bums me out. I want a Cougar-Man skin!