Fallout 3 is such an awesome game, everyone I know who has played it has played it more than once: You start off Good, then you try the Evil route. But what about a third option? A blogger at Afrogamer has a unique play style: Genocide -- that is, killing every NPC in the entire game, whether it's Tenpenny, that half-tree dude or the slaves who just want to be free.
More than just an exercise in nihilism, the experiment also provides unique gameplay challenges: Dead men give no quests, so leveling is a challenge and combat is hard. Recent posts on the blog provide an entertaining and disturbing narrative of a Fallout 3 player who's gone completely off the rails into wholesale slaughter. It's obviously full of spoilers, but if you haver a few minutes and like a good read, head on over and check it out.