On paper, this sounds like a lovely strategy, though perhaps a bit idealistic. Superman 64 was a crap game with crap marketing and crap review scores, but it sold very well. Compare that to a highly-regarded title like Ico, which didn't exactly set the world on fire with its sales, despite its excellent review scores. THQ has also had great success with its Nickelodeon games, which aren't always the best in terms of quality, but do a strong job at serving a younger audience.
While it's great that THQ is committed to making "great games", I don't know if focusing on "bigger titles" that get "high review scores" is the thing to do. Frankly, other publishers are in a position to gun down its big efforts (that don't involve WWE). Perhaps finding an unserved audience would be smarter than going all in.